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The GSH levels of the BSO-treated cells quantified using our RT-based flow cytometry method is well correlated to the values measured using cell lysates with a glutathione reductase-based biochemical assay ( R 2 =0.99, Fig
**Detoxification:** Glutathione is essential for liver detoxification, ensuring the body gets rid of harmful substances efficiently.4
First, G6PD-derived NADPH is a necessary cofactor for fatty acid synthesis and deficiency in NADPH may therefore lead to impairment and cell death
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